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Outlook Hyperlipidemia, or high cholesterol, refers to high levels of fat proteins in the blood. The condition can affect one fat protein or several. Most people will have no symptoms, but having hyperlipidemia increases the risk of developing heart disease.
It affects 1 in 3 Americans. Genetic predisposition, cigarette smoking, obesitypoor diet, and an inactive lifestyle can all lead to hyperlipidemia. Cholesterol and lipoproteins are not the same, although they work together.
Lipoproteins carry cholesterol to the cells. Usually, there are no symptoms with hyperlipidemia, but it can be detected by a simple blood test. Fast facts on hyperlipidemia Here are some key points about hyperlipidemia.
More detail is in the main article. Hyperlipidemia is a major risk factor for heart disease, the leading cause of death in the U. Hypothyroidisma high-fat diet, and being overweight contribute to high cholesterol. Hyperlipidemia means there is too much cholesterol in the blood.
Cholesterol is a waxy fat protein made by the liver. It is essential for healthy cell membranes, brain functioning, hormone production, and vitamin storage. Cholesterol becomes a problem when too much bad cholesterol, or low-density lipoprotein LDLis produced or ingested through unhealthy foods.
Lipoproteins transport cholesterol through the blood to the cells. HDL is good because it carries extra cholesterol back to the liver where it can be eliminated. LDL is bad because it enables excess cholesterol to build up in the blood.
Triglycerides are a type of fat in the blood. These are different from cholesterol, but because of their strong association with heart disease, triglycerides are also measured. A person with hyperlipidemia may have high levels of both LDL and triglycerides.
Symptoms A person with hyperlipidemia usually has no signs or symptoms. In familial, or inherited, hyperlipidemia, there may be yellowish fatty growths around the eyes or the joints. Hyperlipidemia is usually detected during a routine blood test, or following a cardiovascular event, such as a heart attack or stroke.
Excessive fat in the blood accumulates over time, forming plaques on the walls of the arteries and blood vessels. This narrows the openings, producing unstable blood flow through the vessels. The heart has to work harder to pump the blood through the constricted areas.
Treatment Self-management is one way to reduce levels of lipoproteins in the blood. However, in some cases, self-managing hyperlipidemia may not be effective.
In these cases, other treatment options may be required. Medications To determine if and when medications are needed, a physician will look at: There are also new medications called PCSK9 inhibitors being studied for people with cardiovascular disease that need additional lowering of their LDL.
Occasionally, statins are not tolerated, due to the side effects of muscle pain, and people stop taking them. However, it is worth balancing the risk of a cardiovascular event against the risk of side effects before stopping the medication and talking with your doctor about the side effects.
Hyperlipidemia is a common health problem that can lead to serious cardiovascular or heart disease, but it can be prevented and treated through the appropriate use of medication and maintenance of a heart-healthy lifestyle.
Diagnosis Hyperlipidemia is screened using a blood test called a lipid profile. It is important to have nothing to eat or drink for 9 to 12 hours before the test.
Screening may start at the age of 20 years for men at high risk, and later for lower-risk men and women.
If the result is normal, it should be repeated at least every 5 years. A normal lipid profile consists of the following levels: Causes The causes of hyperlipidemia can be due to: This is known as primary hyperlipidemia.
Poor diet and other factors:In response to the request of the NHBPEP Chair and Director of the National Heart, Lung, and Blood Institute (NHLBI) regarding the need to update the JNC 7 report,2 some NHBPEP Coordinating Committee members suggested that the NHBPEP Working Group Report on Hypertension in Children and Adolescents should be revisited.
The Disease Management is an online medical reference, designed to provide nationally established treatment guidelines for the most commonly seen diseases and conditions.
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